Cisplatin and electrolyte abnormalities

WebJun 26, 2024 · Nephrotoxicity-indicated by high serum creatinine, low estimated glomerular filtration rate (eGFR), and/or electrolyte abnormalities, appears in about one-third of … WebApr 12, 2024 · In cancer patients, electrolyte disorders are frequent due to tubular functional abnormalities related to chemotherapeutic drugs, the TLS and the impaired secretion of antidiuretic hormone ... As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced ...

RETRACTED ARTICLE: Urinary parameters predictive and electrolyte ...

WebIn patients with gynecologic cancers, treated with cisplatin or cisplatin in combination with paclitaxel, a higher incidence of nephrotoxicity in the combination group was noted. 414 In addition, ... Electrolyte abnormalities that may either increase the toxicity of concomitant agents (hypokalemia in patients receiving digoxin) or may be ... WebOct 19, 2024 · Severe electrolyte abnormalities during cisplatin were associated with having 2–6-month CKD or hypertension (adjusted odds ratio (AdjOR) [95% CI]: 2.65 [1.04–6.74]). Having both AKI and severe electrolyte abnormalities was associated with 2–6-month hypertension (AdjOR [95% CI]: 3.64 [1.05–12.62]). Conclusions diamond ring stock photos https://kuba-design.com

Profound hyponatremia and dehydration: A case of cisplatin …

WebA slight electrolyte imbalance may not cause noticeable changes. When problems occur, you may experience: Confusion and irritability. Diarrhea or constipation. Fatigue. Headaches. Irregular or fast heart rate (arrhythmia). Muscle cramps, muscle spasms or weakness. Nausea and vomiting. Numbness or tingling in limbs, fingers and toes. WebMay 1, 2024 · The most common diagnoses were central nervous system tumors (58 [36%]), neuroblastoma (43 [27%]), and osteosarcoma (33 [21%]). Acute kidney injury (by serum creatinine level increase) occurred in 48 of 159 patients (30%) at early cisplatin infusions and 23 of 143 patients (16%) at late cisplatin infusions. Webcisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric Dosage … cisco ip dhcp snooping

Hypomagnesemia - Endocrine and Metabolic Disorders - Merck …

Category:Acute kidney injury during cisplatin therapy and ... - Springer

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Cisplatin and electrolyte abnormalities

Phase I trial of daily triapine in combination with cisplatin

WebJul 18, 2024 · Cisplatin causes hypomagnesemia in a dose-dependent fashion and affects up to 90% of patients if no preventive measures are taken (see Section 5 below). 79 The etiology of cisplatin-induced hypomagnesemia is not completely understood; renal Mg loss is the primary mechanism, but gastrointestinal losses have also been reported. 80 … WebJan 17, 2015 · In this research, we focused only on electrolyte abnormalities following cisplatin toxicity, to predict electrolyte abnormalities occurred in dogs treated with cisplatin. The present study was carried out to evaluate renal function of dogs administered with cisplatin 0.75 mg/kg/day for 5 consecutive days with assaying of electrolytes and …

Cisplatin and electrolyte abnormalities

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WebAug 18, 2024 · Mannitol, given as a hypertonic solution, is primarily used in the treatment of cerebral edema and glaucoma. Although generally well tolerated, a variety of fluid, electrolyte, and kidney complications can occur if the patient is not carefully monitored. (See "Evaluation and management of elevated intracranial pressure in adults", section on ... WebNational Center for Biotechnology Information

WebFurosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, ... Abnormalities should be corrected or the drug temporarily withdrawn. Other medications may also influence serum electrolytes. ... There is a risk of ototoxic effects if cisplatin and ... Web• Hypomagnesemia and Accompanying Electrolyte Abnormalities: Monitor during treatment and for at least 8 weeks following the completion. Replete electrolytes as necessary. (5.6) ... and Cisplatin . 5.6 Hypomagnesemia and Accompanying Electrolyte Abnormalities . 5.7 Increased Tumor Progression, Increased Mortality, or Lack ...

WebMay 24, 2006 · This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Cisplatin is a well-known nephrotoxic antineoplastic … WebMay 18, 2024 · Compared with young patients, the incidences of cisplatin-induced nephrotoxicity and acute kidney injury (AKI) in elderly patients are significantly increased, …

WebBlood test results showing low levels may lead to: irregular heartbeat, confusion, blood pressure changes, nervous system or bone disorders. Blood test results showing high …

WebMay 24, 2006 · Conclusion: Cisplatin can cause permanent nephrotoxicity, including Gitelman-like syndrome. This drug should be considered among the possible causes of chronic unexplained electrolyte disorders. Publication types Case Reports Review MeSH terms Adult Alkalosis / chemically induced* Antineoplastic Agents / adverse effects* cisco ip inspect nameWebJul 20, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, … diamond ring stone shapesWebDec 15, 2024 · An electrolyte imbalance occurs when your body’s mineral levels are too high or too low. This can negatively affect vital body systems. Electrolytes must be evenly balanced for your body to... cisco ipics instant connectWebSep 18, 2024 · NCBI Bookshelf diamond ring stores nycWebNov 1, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, hypophosphatemia, hypocalcemia and hyponatremia. diamond ring strainWebNov 1, 2024 · Vaughn E. Dobalian Abstract and Figures Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia,... diamond ring stores in my areaWebelectrolyte imbalance (hyponatremia, hypochloremic alkalosis, hypokalemia, hypomagnesemia ... (with abnormalities of the fasting and 2-hour postprandial sugar) have been observed, and rarely, precipitation of diabetes mellitus has been reported. ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, diamond ring stores online