Recurrent platinum resistant ovarian cancer
WebWeekly topotecan for recurrent platinum resistant ovarian cancer Weekly topotecan is a well-tolerated and effective regimen for platinum-resistant ovarian cancer with considerable less hematological toxicity when compared with historical data for the 5-day regimen. WebThe RR of these agents is in the 10–15% range and overall survival of platinum-resistance ovarian cancer patients is around 12 months. 18 PARP inhibitors as maintenance therapy can improve the prognosis of patients, but the efficacy of monotherapy for platinum-resistance ovarian cancer is still limited. 8,9 It is urgent to explore new ...
Recurrent platinum resistant ovarian cancer
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WebJun 6, 2024 · Results from the company's Phase 2 study in patients with recurrent, platinum-resistant ovarian cancer will be featured in an oral presentation at the ASCO Annual Meeting today. WebApr 8, 2024 · In November 2014, the US Food and Drug Administration (FDA) approved bevacizumab (Avastin) for platinum-resistant, recurrent, epithelial ovarian, fallopian tube, or peritoneal cancers in patients who received no more than two prior chemotherapy regimens. It is indicated in combination with paclitaxel, pegylated liposomal doxorubicin, or topotecan.
WebOct 24, 2007 · Mayo Clinic has reported promising interim results from a Phase II trial of a new combination therapy for patients with recurrent ovarian cancer that is resistant to … WebPlatinum-resistant recurrent ovarian cancer has a poor prognosis, but combined therapy with bevacizumab and anticancer agents may be useful. We report a patient with long-term disease control by the combination of bevacizumab and gemcitabine (BEV + GEM). The patient was a 77-year-old woman with high-grade Stage IIIC serous ovarian carcinoma.
WebPatients with recurrent and platinum-resistant ovarian cancer were treated with the hypomethylating agent decitabine, followed by carboplatin. The expression levels of 78 … WebMar 4, 2024 · Platinum resistant means your cancer comes back within 6 months of finishing your last carboplatin treatment. Your doctor might describe your cancer as: …
WebFeb 23, 2024 · The problem with platinum resistant recurring ovarian cancer is that it has a poor prognosis. It also has a short OS (less than 12 months). Treatment options for these cases are limited and do not prolong survival. Treatments for Platinum-resistant Ovarian Cancer The commonly used treatments are PLD, topotecan, paclitaxel, and gemcitabine.
WebMar 31, 2024 · “In this large, randomized study, women with recurrent, platinum-resistant ovarian cancer who were administered relacorilant at the time they received nab-paclitaxel exhibited meaningful... half format iconWebFeb 2, 2024 · Monk: Recurrent ovarian cancer remains a high unmet need because [essentially] every patient who gets it dies. It is a terminal condition. We have historically bifurcated into 2 groups, platinum-resistant [disease] and platinum-sensitive [disease, and we’ve] evolved that terminology into those who are eligible for platinum and those who … half formed golem diablo 3WebSep 16, 2024 · Platinum-resistant recurrent ovarian cancer (PROC): the patient was diagnosed with platinum-resistant recurrence for the first time. PROC refers to the … bum run torontoWebA dose-escalation phase 1b study of alpelisib (a PI3K inhibitor) and olaparib demonstrated that among 28 women with epithelial ovarian cancer, 82% of whom had platinum-resistant disease, 36% had a partial response (median 5.5 months) and 50% had stable disease. 43 It should be noted that this was not the primary endpoint of the study. However ... bum rush defWebApr 11, 2024 · BackgroundThere are a variety of treatment options for recurrent platinum-resistant ovarian cancer, and the optimal specific treatment still remains to be … bumrungrad international hospital reviewsWebApr 1, 2024 · Apr 1, 2024. Ariana Pelosci. The addition of relacorilant to nab-paclitaxel has improved overall survival in patients with recurrent, platinum-resistant ovarian cancer. A survival benefit was observed in patients with recurrent, platinum-resistant ovarian cancer who were treated with relacorilant (CORT-125134) plus nab-paclitaxel, according to ... half formed ghost analysis war photographerWebMay 28, 2024 · If you previously received platinum-based chemotherapy to treat the cancer and your last dose of chemo was administered within the past 6 months, the cancer will … half formulated