WebFeb 18, 2024 · Pulmonary hypertension (PH) is a chronic and progressive disease caused by obstructions and functional changes of small pulmonary arteries. Current treatment options of PH are costly with patients needing long-term taking medicine. The traditional Chinese … Objective. This study is aimed at exploring the molecular mechanism of Shufeiya recipe in the treatment of pulmonary hypertension (PH) using network pharmacology and molecular docking analysis. Methods. Active components and their target proteins in the recipe were screened using the TCMSP … See more Pulmonary hypertension (PH) is a chronic progressive pulmonary vascular system disease caused by pulmonary arteriole obstruction, and it is characterized by pulmonary artery … See more A total of 67 active components of Shufeiya recipe were obtained from the TCMSP database, including 3 active components from platycodi radix, 52 active components from Salvia miltiorrhiza, 10 active … See more Based on the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) (http://tcmspw.com/tcmsp.php) [ 1. J. Ru, P. Li, J. Wang et al., “TCMSP: a database of systems … See more The occurrence of PH is closely related to abnormalities in the pulmonary vascular function and/or structure. Long-term hypoxia or other factors damage the endothelial cell … See more
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WebDownload scientific diagram Shufeiya Recipe inhibited the Ras/ERK signaling pathway of PH rats. (a, b) Moderate and high groups of Shufeiya Recipe downregulated the relative immunofluorescence ... WebApr 1, 2016 · Shufeiya Recipe Improves Monocrotaline-Induced Pulmonary Hypertension in Rats by Regulating SIRT3/FOXO3a and Its Downstream Signaling Pathways. Zhuangzhuang Jia, Haifeng Yan, Shuai Wang, Lin Wang and Yawen Cao et al. 18 Feb 2024 Disease Markers, Vol. 2024. small canstruction ideas
Network Pharmacology and Molecular Docking Analysis of …
WebDownload scientific diagram Shufeiya Recipe upregulated concentration of NO, sGC, and cGMP and the protein expression level of PKG in PH rats. (a) Moderate and high groups of Shufeiya Recipe ... WebThe traditional Chinese medicine (TCM) compound "Shufeiya Recipe" was used to intervene in monocrotaline- (MCT-) induced pulmonary hypertension in rats. The rats were randomly divided into the control group, model group, positive drug (Sildenafil) group, and Shufeiya Recipe low-, moderate-, and high-dose groups. some practical information